rethinkPeptides Search
Menu
Study breakdown

Lactoferricin's Loop Structure Determines Its Ability to Kill Leukemia Cells

evidence
The takeaway

The loop structure of bovine lactoferricin was critical for inducing apoptosis in Jurkat leukemia cells, with loop disruption eliminating anticancer activity — structural requirements for cancer cell killing.

Key finding

The loop structure of bovine lactoferricin was critical for inducing apoptosis in Jurkat leukemia cells, with loop disruption eliminating anticancer a

What the researchers found

The loop structure of bovine lactoferricin was critical for inducing apoptosis in Jurkat leukemia cells, with loop disruption eliminating anticancer activity — structural requirements for cancer cell killing.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Lactoferricin's Loop Structure Determines Its Ability to Kill Leukemia Cells
What was found?
The loop structure of bovine lactoferricin was critical for inducing apoptosis in Jurkat leukemia cells, with loop disruption eliminating anticancer activity — structural requirements for cancer cell killing.

Read the original research

Effect of loop structure of bovine lactoferricin on apoptosis in Jurkat cells.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 23(3), 555-61

Citation

Zhang, Tie-nan; Yang, Wei; Liu, Ning. (2010). Effect of loop structure of bovine lactoferricin on apoptosis in Jurkat cells.. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 23(3), 555-61. https://doi.org/10.1007/s10534-010-9324-2