Opioid Peptides Affect Cancer Cell Movement, Invasion, and Metastasis
Opioid peptides and receptor activation affected cancer cell migration, chemotaxis, invasion, and adhesion — potentially influencing metastatic behavior, with effects depending on opioid type and cancer cell context.
Quick Facts
What This Study Found
Opioid peptides modulated cancer cell migration, chemotaxis, invasion, and adhesion in a peptide-type and cancer-type dependent manner, suggesting the opioid system influences metastatic behavior — with implications for opioid drug use in cancer patients.
Key Numbers
How They Did This
in-vitro study.
Why This Research Matters
Relevant for opioid-peptides, cancer.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Opioid peptides modulated cancer cell migration, chemotaxis, invasion, and adhesion in a peptide-type and cancer-type dependent manner, suggesting the
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2007.
- Original Title:
- Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.
- Published In:
- Neuropeptides, 41(6), 441-52 (2007)
- Authors:
- Zagon, Ian S(3), Rahn, Kristen A, McLaughlin, Patricia J(3)
- Database ID:
- RPEP-01308
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Opioid Peptides Affect Cancer Cell Movement, Invasion, and Metastasis
What was found?
Opioid peptides and receptor activation affected cancer cell migration, chemotaxis, invasion, and adhesion — potentially influencing metastatic behavior, with effects depending on opioid type and cancer cell context.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01308APA
Zagon, Ian S; Rahn, Kristen A; McLaughlin, Patricia J. (2007). Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.. Neuropeptides, 41(6), 441-52.
MLA
Zagon, Ian S, et al. "Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.." Neuropeptides, 2007.
RethinkPeptides
RethinkPeptides Research Database. "Opioids and migration, chemotaxis, invasion, and adhesion of..." RPEP-01308. Retrieved from https://rethinkpeptides.com/research/zagon-2007-opioids-and-migration-chemotaxis
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.