Opioid peptides and receptor activation affected cancer cell migration, chemotaxis, invasion, and adhesion — potentially influencing metastatic behavior, with effects depending on opioid type and cancer cell context.
Key findingOpioid peptides modulated cancer cell migration, chemotaxis, invasion, and adhesion in a peptide-type and cancer-type dependent manner, suggesting the
What the researchers found
Opioid peptides modulated cancer cell migration, chemotaxis, invasion, and adhesion in a peptide-type and cancer-type dependent manner, suggesting the opioid system influences metastatic behavior — with implications for opioid drug use in cancer patients.
Why it matters
Relevant for opioid-peptides, cancer.
How the study worked
in-vitro study.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.
Neuropeptides, 41(6), 441-52
Citation
Zagon, Ian S; Rahn, Kristen A; McLaughlin, Patricia J. (2007). Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.. Neuropeptides, 41(6), 441-52.