This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
DDAVP did not significantly affect platelet aggregation in dogs treated with clopidogrel.
Why it matters
Understanding how DDAVP affects platelet function can help veterinarians make informed decisions about treating dogs with clotting disorders. This study indicates that DDAVP may not be beneficial for dogs on clopidogrel.
How the study worked
The study was a randomized double-blinded crossover design involving 7 healthy dogs, with platelet function assessed using impedance aggregometry before and after treatment with DDAVP.
What this study cannot tell us
The small sample size of 7 dogs limits the generalizability of the findings.
Read the original research
The use of impedance aggregometry to evaluate platelet function after the administration of DDAVP in healthy dogs treated with aspirin or clopidogrel.
American journal of veterinary research, 82(10), 823-828
Citation
Yankin, Igor; Carver, Andy M; Koenigshof, Amy M. (2021). The use of impedance aggregometry to evaluate platelet function after the administration of DDAVP in healthy dogs treated with aspirin or clopidogrel.. American journal of veterinary research, 82(10), 823-828. https://doi.org/10.2460/ajvr.82.10.823