Arginine Vasopressin Boosts Brain Enkephalin and Endorphin Production in the Pain-Control Center
AVP enhanced synthesis and secretion of met-enkephalin and beta-endorphin in the periaqueductal gray (PAG) — the brain's primary pain control center — revealing a vasopressin-opioid interaction for pain modulation.
Quick Facts
What This Study Found
Arginine vasopressin stimulated enkephalin and endorphin synthesis and secretion in the periaqueductal gray, demonstrating vasopressin-opioid peptide cross-talk in the brain's primary descending pain modulation center.
Key Numbers
How They Did This
in-vitro study on opioid-peptides, neuropeptides.
Why This Research Matters
Relevant for opioid-peptides, neuropeptides, pain.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Arginine vasopressin stimulated enkephalin and endorphin synthesis and secretion in the periaqueductal gray, demonstrating vasopressin-opioid peptide
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the rat.
- Published In:
- Brain research bulletin, 71(1-3), 193-9 (2006)
- Authors:
- Yang, Jun(8), Yang, Yu(7), Xu, Hong-Tao, Chen, Jian-Min, Liu, Wen-Yan, Lin, Bao-Chen
- Database ID:
- RPEP-01195
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Arginine Vasopressin Boosts Brain Enkephalin and Endorphin Production in the Pain-Control Center
What was found?
AVP enhanced synthesis and secretion of met-enkephalin and beta-endorphin in the periaqueductal gray (PAG) — the brain's primary pain control center — revealing a vasopressin-opioid interaction for pain modulation.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01195APA
Yang, Jun; Yang, Yu; Xu, Hong-Tao; Chen, Jian-Min; Liu, Wen-Yan; Lin, Bao-Chen. (2006). Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the rat.. Brain research bulletin, 71(1-3), 193-9.
MLA
Yang, Jun, et al. "Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the rat.." Brain research bulletin, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Arginine vasopressin enhances periaqueductal gray synthesis ..." RPEP-01195. Retrieved from https://rethinkpeptides.com/research/yang-2006-arginine-vasopressin-enhances-periaqueductal
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.