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Study breakdown

Japanese Herbal Medicine and Ghrelin Together Improve Chemotherapy-Induced Appetite Loss

evidence
The takeaway

Rikkunshito (traditional medicine) combined with serotonin 5-HT2C receptor antagonism improved cisplatin-induced appetite loss through hypothalamic ghrelin pathway enhancement — integrating traditional and pharmacological approaches.

Key finding

Rikkunshito (traditional medicine) combined with serotonin 5-HT2C receptor antagonism improved cisplatin-induced appetite loss through hypothalamic gh

What the researchers found

Rikkunshito (traditional medicine) combined with serotonin 5-HT2C receptor antagonism improved cisplatin-induced appetite loss through hypothalamic ghrelin pathway enhancement — integrating traditional and pharmacological approaches.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Japanese Herbal Medicine and Ghrelin Together Improve Chemotherapy-Induced Appetite Loss
What was found?
Rikkunshito (traditional medicine) combined with serotonin 5-HT2C receptor antagonism improved cisplatin-induced appetite loss through hypothalamic ghrelin pathway enhancement — integrating traditional and pharmacological approaches.

Read the original research

Rikkunshito and 5-HT2C receptor antagonist improve cisplatin-induced anorexia via hypothalamic ghrelin interaction.

Regulatory peptides, 161(1-3), 97-105

Citation

Yakabi, Koji; Kurosawa, Susumu; Tamai, Mitsuo; Yuzurihara, Mitsutoshi; Nahata, Miwa; Ohno, Shino; Ro, Shoki; Kato, Shingo; Aoyama, Toru; Sakurada, Tomoya; Takabayashi, Hidehiko; Hattori, Tomohisa. (2010). Rikkunshito and 5-HT2C receptor antagonist improve cisplatin-induced anorexia via hypothalamic ghrelin interaction.. Regulatory peptides, 161(1-3), 97-105. https://doi.org/10.1016/j.regpep.2010.02.003