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Lactoferricin Peptides Block Pseudomonas Biofilms AND Virulence Factors

evidence
The takeaway

Lactoferricin-derived peptides and LFchimera inhibited both biofilm formation and virulence factor production in Pseudomonas aeruginosa — anti-virulence activity that disarms rather than just kills this dangerous pathogen.

Key finding

Lactoferricin-derived peptides and LFchimera inhibited both biofilm formation and virulence factor production in Pseudomonas aeruginosa — anti-virulen

What the researchers found

Lactoferricin-derived peptides and LFchimera inhibited both biofilm formation and virulence factor production in Pseudomonas aeruginosa — anti-virulence activity that disarms rather than just kills this dangerous pathogen.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Lactoferricin Peptides Block Pseudomonas Biofilms AND Virulence Factors
What was found?
Lactoferricin-derived peptides and LFchimera inhibited both biofilm formation and virulence factor production in Pseudomonas aeruginosa — anti-virulence activity that disarms rather than just kills this dangerous pathogen.

Read the original research

Lactoferrin-derived peptides and Lactoferricin chimera inhibit virulence factor production and biofilm formation in Pseudomonas aeruginosa.

Journal of applied microbiology, 109(4), 1311-8

Citation

Xu, G; Xiong, W; Hu, Q; Zuo, P; Shao, B; Lan, F; Lu, X; Xu, Y; Xiong, S. (2010). Lactoferrin-derived peptides and Lactoferricin chimera inhibit virulence factor production and biofilm formation in Pseudomonas aeruginosa.. Journal of applied microbiology, 109(4), 1311-8. https://doi.org/10.1111/j.1365-2672.2010.04751.x