Inhibitory effect of LL-37 and human lactoferricin on growth and biofilm formation of anaerobes associated with oral diseases.
Quick Facts
What This Study Found
LL-37 inhibited growth and biofilm formation of oral bacteria with p < 0.0001; LfcinH had minimal effect.
Key Numbers
How They Did This
The study involved incubating bacterial suspensions with varying concentrations of LL-37 and Lactoferricin, followed by measuring growth and biofilm formation using specific assays.
Why This Research Matters
Understanding how these peptides work could lead to new treatments for oral diseases. LL-37 shows potential as a therapeutic option, while Lactoferricin may not be suitable for this purpose.
What This Study Doesn't Tell Us
The study did not fully elucidate the mechanisms of action for the AMPs, and Lactoferricin showed limited effectiveness.
Trust & Context
- Original Title:
- Inhibitory effect of LL-37 and human lactoferricin on growth and biofilm formation of anaerobes associated with oral diseases.
- Published In:
- Anaerobe, 67, 102301 (2021)
- Database ID:
- RPEP-05882
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-05882APA
Wuersching, Sabina Noreen; Huth, Karin Christine; Hickel, Reinhard; Kollmuss, Maximilian. (2021). Inhibitory effect of LL-37 and human lactoferricin on growth and biofilm formation of anaerobes associated with oral diseases.. Anaerobe, 67, 102301. https://doi.org/10.1016/j.anaerobe.2020.102301
MLA
Wuersching, Sabina Noreen, et al. "Inhibitory effect of LL-37 and human lactoferricin on growth and biofilm formation of anaerobes associated with oral diseases.." Anaerobe, 2021. https://doi.org/10.1016/j.anaerobe.2020.102301
RethinkPeptides
RethinkPeptides Research Database. "Inhibitory effect of LL-37 and human lactoferricin on growth..." RPEP-05882. Retrieved from https://rethinkpeptides.com/research/wuersching-2021-inhibitory-effect-of-ll37
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.