This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
LL-37 inhibited growth and biofilm formation of oral bacteria with p < 0.0001; LfcinH had minimal effect.
Why it matters
Understanding how these peptides work could lead to new treatments for oral diseases. LL-37 shows potential as a therapeutic option, while Lactoferricin may not be suitable for this purpose.
How the study worked
The study involved incubating bacterial suspensions with varying concentrations of LL-37 and Lactoferricin, followed by measuring growth and biofilm formation using specific assays.
What this study cannot tell us
The study did not fully elucidate the mechanisms of action for the AMPs, and Lactoferricin showed limited effectiveness.
Read the original research
Inhibitory effect of LL-37 and human lactoferricin on growth and biofilm formation of anaerobes associated with oral diseases.
Anaerobe, 67, 102301
Citation
Wuersching, Sabina Noreen; Huth, Karin Christine; Hickel, Reinhard; Kollmuss, Maximilian. (2021). Inhibitory effect of LL-37 and human lactoferricin on growth and biofilm formation of anaerobes associated with oral diseases.. Anaerobe, 67, 102301. https://doi.org/10.1016/j.anaerobe.2020.102301