Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation.
Quick Facts
What This Study Found
SVHRP treatment significantly reduced iNOS and TNF-α levels in LPS-injected mice and cell cultures.
Key Numbers
How They Did This
The study used an animal model with LPS-induced neuroinflammation and primary brain cell cultures to assess the effects of SVHRP on inflammatory markers.
Why This Research Matters
Understanding how SVHRP works could lead to new treatments for neuroinflammatory conditions, which are linked to various brain disorders.
What This Study Doesn't Tell Us
The study was conducted in animal models, which may not fully replicate human responses.
Trust & Context
- Original Title:
- Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation.
- Published In:
- Frontiers in pharmacology, 12, 704715 (2021)
- Authors:
- Wu, Xue-Fei, Li, Chun, Yang, Guang, Wang, Ying-Zi, Peng, Yan, Zhu, Dan-Dan, Sui, Ao-Ran, Wu, Qiong, Li, Qi-Fa, Wang, Bin, Li, Na, Zhang, Yue, Ge, Bi-Ying, Zhao, Jie, Li, Shao
- Database ID:
- RPEP-05880
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-05880APA
Wu, Xue-Fei; Li, Chun; Yang, Guang; Wang, Ying-Zi; Peng, Yan; Zhu, Dan-Dan; Sui, Ao-Ran; Wu, Qiong; Li, Qi-Fa; Wang, Bin; Li, Na; Zhang, Yue; Ge, Bi-Ying; Zhao, Jie; Li, Shao. (2021). Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation.. Frontiers in pharmacology, 12, 704715. https://doi.org/10.3389/fphar.2021.704715
MLA
Wu, Xue-Fei, et al. "Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation.." Frontiers in pharmacology, 2021. https://doi.org/10.3389/fphar.2021.704715
RethinkPeptides
RethinkPeptides Research Database. "Scorpion Venom Heat-Resistant Peptide Attenuates Microglia A..." RPEP-05880. Retrieved from https://rethinkpeptides.com/research/wu-2021-scorpion-venom-heatresistant-peptide
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.