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Study breakdown

Designing a Custom Anticancer Peptide: CB1a Structure and Function Against Tumor Cells

evidence
The takeaway

CB1a, a rationally designed anticancer peptide, showed selective tumor cell killing through membrane disruption with characterized 3D structure — demonstrating successful de novo anticancer peptide engineering.

Key finding

CB1a, a rationally designed anticancer peptide, showed selective tumor cell killing through membrane disruption with characterized 3D structure — demo

What the researchers found

CB1a, a rationally designed anticancer peptide, showed selective tumor cell killing through membrane disruption with characterized 3D structure — demonstrating successful de novo anticancer peptide engineering.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Designing a Custom Anticancer Peptide: CB1a Structure and Function Against Tumor Cells
What was found?
CB1a, a rationally designed anticancer peptide, showed selective tumor cell killing through membrane disruption with characterized 3D structure — demonstrating successful de novo anticancer peptide engineering.

Read the original research

Structure and function of a custom anticancer peptide, CB1a.

Peptides, 30(5), 839-48

Citation

Wu, Jiun-Ming; Jan, Pey-Shynan; Yu, Hui-Chen; Haung, Hsu-Yuang; Fang, Huey-Jen; Chang, Yuan-I; Cheng, Jya-Wei; Chen, Hueih Min. (2009). Structure and function of a custom anticancer peptide, CB1a.. Peptides, 30(5), 839-48. https://doi.org/10.1016/j.peptides.2009.02.004