Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus.
Quick Facts
What This Study Found
The synthetic α-[P9K] conotoxin OI showed a 2.85 to 18.4 fold increase in potency.
Key Numbers
How They Did This
The study involved isolating and synthesizing conotoxins, creating analogs with mutations and modifications, and testing their effects on specific receptors.
Why This Research Matters
This research could lead to the development of new pain relief medications based on conotoxins, which may offer alternatives to current treatments.
What This Study Doesn't Tell Us
The study primarily focuses on in vitro assays, and results may not directly translate to clinical applications in humans.
Trust & Context
- Original Title:
- Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus.
- Published In:
- International journal of molecular sciences, 23(20) (2022)
- Authors:
- Wiere, Sean, Sugai, Christopher, Espiritu, Michael J, Aurelio, Vincent P, Reyes, Chloe D, Yuzon, Nicole, Whittal, Randy M, Tytgat, Jan, Peigneur, Steve, Bingham, Jon-Paul
- Database ID:
- RPEP-06591
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06591APA
Wiere, Sean; Sugai, Christopher; Espiritu, Michael J; Aurelio, Vincent P; Reyes, Chloe D; Yuzon, Nicole; Whittal, Randy M; Tytgat, Jan; Peigneur, Steve; Bingham, Jon-Paul. (2022). Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus.. International journal of molecular sciences, 23(20). https://doi.org/10.3390/ijms232012096
MLA
Wiere, Sean, et al. "Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus.." International journal of molecular sciences, 2022. https://doi.org/10.3390/ijms232012096
RethinkPeptides
RethinkPeptides Research Database. "Research into the Bioengineering of a Novel α-Conotoxin from..." RPEP-06591. Retrieved from https://rethinkpeptides.com/research/wiere-2022-research-into-the-bioengineering
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.