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Lixisenatide: A New GLP-1 Drug for Type 2 Diabetes With Distinct Pharmacological Properties

evidence
The takeaway

Lixisenatide (a new GLP-1 receptor agonist based on exendin-4) showed distinct pharmacological properties from liraglutide/exenatide: stronger post-meal glucose control with convenient once-daily dosing.

Key finding

Lixisenatide (a new GLP-1 receptor agonist based on exendin-4) showed distinct pharmacological properties from liraglutide/exenatide: stronger post-me

What the researchers found

Lixisenatide (a new GLP-1 receptor agonist based on exendin-4) showed distinct pharmacological properties from liraglutide/exenatide: stronger post-meal glucose control with convenient once-daily dosing.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Lixisenatide: A New GLP-1 Drug for Type 2 Diabetes With Distinct Pharmacological Properties
What was found?
Lixisenatide (a new GLP-1 receptor agonist based on exendin-4) showed distinct pharmacological properties from liraglutide/exenatide: stronger post-meal glucose control with convenient once-daily dosing.

Read the original research

Pharmacological profile of lixisenatide: A new GLP-1 receptor agonist for the treatment of type 2 diabetes.

Regulatory peptides, 164(2-3), 58-64

Citation

Werner, Ulrich; Haschke, Guido; Herling, Andreas W; Kramer, Werner. (2010). Pharmacological profile of lixisenatide: A new GLP-1 receptor agonist for the treatment of type 2 diabetes.. Regulatory peptides, 164(2-3), 58-64. https://doi.org/10.1016/j.regpep.2010.05.008