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Potent Inhibition of Human Betacoronaviruses by a Short Double-Stapled Peptide Mimicking the HR2 Core Region in Viral Spike Protein.

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Potent Inhibition of Human Betacoronaviruses by a Short Double-Stapled Peptide Mimicking the HR2 Core Region in Viral Spike Protein.

Journal of medicinal chemistry, 68(17), 18625-18640

Citation

Wang, Chao; Li, Qing; Wang, Yuanzhou; Zhang, Wenpeng; Zheng, Longbo; Tu, Jiahuang; Zhou, Jie; Wang, Fei; Yuan, Yu; Xu, Binbin; Xue, Guangpeng; Du, Xinmeng; Yuan, Ming; Du, Shu; Wang, Huan; Zhuang, Xiaomei; Shi, Weiguo; Lu, Lu; Xiao, Junhai; Wang, Qian; Jiang, Shibo. (2025). Potent Inhibition of Human Betacoronaviruses by a Short Double-Stapled Peptide Mimicking the HR2 Core Region in Viral Spike Protein.. Journal of medicinal chemistry, 68(17), 18625-18640. https://doi.org/10.1021/acs.jmedchem.5c01614