Bovine lactoferricin was expressed in Pichia methanolica yeast with retained antimicrobial activity, providing another scalable eukaryotic expression system for commercial antimicrobial peptide production.
Key findingBovine lactoferricin expressed in Pichia methanolica yeast retained antimicrobial activity after purification, establishing methylotrophic yeast as a
What the researchers found
Bovine lactoferricin expressed in Pichia methanolica yeast retained antimicrobial activity after purification, establishing methylotrophic yeast as a eukaryotic expression platform for commercial-scale antimicrobial peptide manufacturing.
Why it matters
Relevant for antimicrobial-peptides, peptide-design.
How the study worked
in-vitro study.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Heterologous expression of bovine lactoferricin in Pichia methanolica.
Biochemistry. Biokhimiia, 72(6), 640-3
Citation
Wang, Haikuan; Zhao, Xinhuai; Lu, Fuping. (2007). Heterologous expression of bovine lactoferricin in Pichia methanolica.. Biochemistry. Biokhimiia, 72(6), 640-3.