Ipamorelin (ghrelin mimetic) improved postoperative ileus in rats, restoring gut motility after surgery — positioning this selective GH secretagogue as a potential treatment for the common problem of post-surgical gut shutdown.
Key findingIpamorelin (ghrelin mimetic) improved postoperative ileus in rats, restoring gut motility after surgery — positioning this selective GH secretagogue a
What the researchers found
Ipamorelin (ghrelin mimetic) improved postoperative ileus in rats, restoring gut motility after surgery — positioning this selective GH secretagogue as a potential treatment for the common problem of post-surgical gut shutdown.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus.
The Journal of pharmacology and experimental therapeutics, 329(3), 1110-6
Citation
Venkova, Kalina; Mann, William; Nelson, Richard; Greenwood-Van Meerveld, Beverley. (2009). Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus.. The Journal of pharmacology and experimental therapeutics, 329(3), 1110-6. https://doi.org/10.1124/jpet.108.149211