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Study breakdown

Age, Belly Fat, IGF-1, and Binding Proteins: How They All Interrelate in Aging

evidence
The takeaway

Novel statistical relationships between age, visceral adiposity, IGF-1, and IGF binding protein concentrations revealed complex multi-directional interactions that change the GH/IGF-1 axis during aging.

Key finding

Novel statistical relationships between age, visceral adiposity, IGF-1, and IGF binding protein concentrations revealed complex multi-directional inte

What the researchers found

Novel statistical relationships between age, visceral adiposity, IGF-1, and IGF binding protein concentrations revealed complex multi-directional interactions that change the GH/IGF-1 axis during aging.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Age, Belly Fat, IGF-1, and Binding Proteins: How They All Interrelate in Aging
What was found?
Novel statistical relationships between age, visceral adiposity, IGF-1, and IGF binding protein concentrations revealed complex multi-directional interactions that change the GH/IGF-1 axis during aging.

Read the original research

Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp.

The Journal of clinical endocrinology and metabolism, 94(6), 2137-43

Citation

Veldhuis, Johannes D; Keenan, Daniel M; Bailey, Joy N; Adeniji, Adebordurin M; Miles, John M; Bowers, Cyril Y. (2009). Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp.. The Journal of clinical endocrinology and metabolism, 94(6), 2137-43. https://doi.org/10.1210/jc.2009-0136