The full-length ghrelin analog BIM-28125 partially reversed glucocorticoid-induced growth suppression in rats, increasing body weight and longitudinal growth despite ongoing steroid treatment.
Key findingGhrelin analog BIM-28125 partially reversed methylprednisolone-induced growth suppression in rats, increasing body weight gain and longitudinal bone g
What the researchers found
Ghrelin analog BIM-28125 partially reversed methylprednisolone-induced growth suppression in rats, increasing body weight gain and longitudinal bone growth during concurrent steroid treatment — supporting ghrelin-based therapy for steroid-treated children's growth.
Why it matters
Relevant for ghrp, hormone-optimization.
How the study worked
animal-study study.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Glucocorticoid inhibition of growth in rats: partial reversal with the full-length ghrelin analog BIM-28125.
Pituitary, 10(3), 267-74
Citation
Tulipano, Giovanni; Taylor, John E; Halem, Heather A; Datta, Rakesh; Dong, Jesse Z; Culler, Michael D; Bianchi, Irene; Cocchi, Daniela; Giustina, Andrea. (2007). Glucocorticoid inhibition of growth in rats: partial reversal with the full-length ghrelin analog BIM-28125.. Pituitary, 10(3), 267-74.