Utilisation of compounds from venoms in drug discovery.
Quick Facts
What This Study Found
Venom-derived compounds have produced successful drugs and represent a largely untapped source of stable molecules for difficult drug targets.
Key Numbers
Approved drugs: exenatide, eptifibatide, echistatin; venom sources from 7+ animal groups
How They Did This
Review article covering venom biology, drug discovery examples, and challenges in developing venom-derived therapeutics.
Why This Research Matters
Many disease targets are too complex for traditional small molecules but too simple for antibodies. Venom peptides fill this gap.
What This Study Doesn't Tell Us
This is a review, not original research. Many venom compounds face challenges in oral absorption, manufacturing, and toxicity.
Trust & Context
- Original Title:
- Utilisation of compounds from venoms in drug discovery.
- Published In:
- Progress in medicinal chemistry, 60, 1-66 (2021)
- Authors:
- Trim, Carol M, Byrne, Lee J, Trim, Steven A
- Database ID:
- RPEP-05827
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-05827APA
Trim, Carol M; Byrne, Lee J; Trim, Steven A. (2021). Utilisation of compounds from venoms in drug discovery.. Progress in medicinal chemistry, 60, 1-66. https://doi.org/10.1016/bs.pmch.2021.01.001
MLA
Trim, Carol M, et al. "Utilisation of compounds from venoms in drug discovery.." Progress in medicinal chemistry, 2021. https://doi.org/10.1016/bs.pmch.2021.01.001
RethinkPeptides
RethinkPeptides Research Database. "Utilisation of compounds from venoms in drug discovery." RPEP-05827. Retrieved from https://rethinkpeptides.com/research/trim-2021-utilisation-of-compounds-from
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.