Dendritic cells transduced with lentiviral VIP vectors became VIP-secreting tolerogenic DCs, creating self-sustaining anti-inflammatory immune cells for autoimmune disease gene therapy.
Key findingDendritic cells transduced with lentiviral VIP vectors became VIP-secreting tolerogenic DCs, creating self-sustaining anti-inflammatory immune cells f
What the researchers found
Dendritic cells transduced with lentiviral VIP vectors became VIP-secreting tolerogenic DCs, creating self-sustaining anti-inflammatory immune cells for autoimmune disease gene therapy.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs.
Molecular therapy : the journal of the American Society of Gene Therapy, 18(5), 1035-45
Citation
Toscano, Miguel G; Delgado, Mario; Kong, Weimin; Martin, Francisco; Skarica, Mario; Ganea, Doina. (2010). Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs.. Molecular therapy : the journal of the American Society of Gene Therapy, 18(5), 1035-45. https://doi.org/10.1038/mt.2009.293