CJC-1295 in Humans: Single Injection Sustains GH and IGF-1 Elevation for Up to 2 Weeks
A single subcutaneous injection of CJC-1295 in healthy humans produced dose-dependent, sustained GH and IGF-1 elevation lasting up to 2 weeks — the longest-acting GH-axis restoration from a single peptide dose.
Quick Facts
What This Study Found
Single SC CJC-1295 injection in healthy adults produced dose-dependent sustained GH pulsatility and IGF-1 elevation lasting 6-14 days depending on dose, with 2-3 fold IGF-1 increase maintained for up to 2 weeks — the most sustained GH-axis restoration from a single peptide dose.
Key Numbers
How They Did This
RCT study on cjc-1295, hormone-optimization.
Why This Research Matters
Relevant for cjc-1295, hormone-optimization.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Single SC CJC-1295 injection in healthy adults produced dose-dependent sustained GH pulsatility and IGF-1 elevation lasting 6-14 days depending on dos
- Evidence Grade:
- strong evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
- Published In:
- The Journal of clinical endocrinology and metabolism, 91(3), 799-805 (2006)
- Authors:
- Teichman, Sam L, Neale, Ann, Lawrence, Betty(2), Gagnon, Catherine, Castaigne, Jean-Paul, Frohman, Lawrence A
- Database ID:
- RPEP-01190
Evidence Hierarchy
Frequently Asked Questions
What was studied?
CJC-1295 in Humans: Single Injection Sustains GH and IGF-1 Elevation for Up to 2 Weeks
What was found?
A single subcutaneous injection of CJC-1295 in healthy humans produced dose-dependent, sustained GH and IGF-1 elevation lasting up to 2 weeks — the longest-acting GH-axis restoration from a single peptide dose.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01190APA
Teichman, Sam L; Neale, Ann; Lawrence, Betty; Gagnon, Catherine; Castaigne, Jean-Paul; Frohman, Lawrence A. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.. The Journal of clinical endocrinology and metabolism, 91(3), 799-805.
MLA
Teichman, Sam L, et al. "Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.." The Journal of clinical endocrinology and metabolism, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Prolonged stimulation of growth hormone (GH) and insulin-lik..." RPEP-01190. Retrieved from https://rethinkpeptides.com/research/teichman-2006-prolonged-stimulation-of-growth
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.