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Infants With Failure to Thrive Have HIGH Ghrelin But Low Appetite — A Ghrelin Resistance Paradox

evidence
The takeaway

Infants with failure to thrive had elevated ghrelin but REDUCED appetite, suggesting ghrelin resistance (the hunger hormone can't do its job) — a paradox explaining why some underweight babies can't eat enough.

Key finding

Infants with failure to thrive had elevated ghrelin but REDUCED appetite, suggesting ghrelin resistance (the hunger hormone can't do its job) — a para

What the researchers found

Infants with failure to thrive had elevated ghrelin but REDUCED appetite, suggesting ghrelin resistance (the hunger hormone can't do its job) — a paradox explaining why some underweight babies can't eat enough.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Infants With Failure to Thrive Have HIGH Ghrelin But Low Appetite — A Ghrelin Resistance Paradox
What was found?
Infants with failure to thrive had elevated ghrelin but REDUCED appetite, suggesting ghrelin resistance (the hunger hormone can't do its job) — a paradox explaining why some underweight babies can't eat enough.

Read the original research

Elevated circulating acylated and total ghrelin concentrations along with reduced appetite scores in infants with failure to thrive.

Pediatric research, 65(5), 569-73

Citation

Tannenbaum, Gloria Shaffer; Ramsay, Maria; Martel, Chantal; Samia, Marwan; Zygmuntowicz, Catherine; Porporino, Mafalda; Ghosh, Shuvo. (2009). Elevated circulating acylated and total ghrelin concentrations along with reduced appetite scores in infants with failure to thrive.. Pediatric research, 65(5), 569-73. https://doi.org/10.1203/PDR.0b013e3181a0ce66