Oxidative stress markers correlated inversely with adiponectin in heart failure patients, with reduced adiponectin associated with worse outcomes — oxidative stress suppresses this protective adipokine.
Key findingPlasma oxidative stress markers inversely correlated with adiponectin levels in CHF patients, with low adiponectin associated with worse outcomes — ox
What the researchers found
Plasma oxidative stress markers inversely correlated with adiponectin levels in CHF patients, with low adiponectin associated with worse outcomes — oxidative stress suppresses the protective adipokine adiponectin, adding metabolic dysfunction to heart failure pathophysiology.
Why it matters
Relevant for cardiovascular.
How the study worked
cross-sectional study.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2008.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Impact of oxidative stress on plasma adiponectin in patients with chronic heart failure.
Circulation journal : official journal of the Japanese Circulation Society, 72(4), 563-8
Citation
Tanaka, Toshinari; Tsutamoto, Takayoshi; Nishiyama, Keizo; Sakai, Hiroshi; Fujii, Masanori; Yamamoto, Takashi; Horie, Minoru. (2008). Impact of oxidative stress on plasma adiponectin in patients with chronic heart failure.. Circulation journal : official journal of the Japanese Circulation Society, 72(4), 563-8.