PACAP (pituitary adenylyl cyclase-activating polypeptide) intrinsically regulated Treg abundance and protected against experimental autoimmune encephalomyelitis (MS model), establishing it as a natural anti-autoimmune neuropeptide.
Key findingPACAP (pituitary adenylyl cyclase-activating polypeptide) intrinsically regulated Treg abundance and protected against experimental autoimmune encepha
What the researchers found
PACAP (pituitary adenylyl cyclase-activating polypeptide) intrinsically regulated Treg abundance and protected against experimental autoimmune encephalomyelitis (MS model), establishing it as a natural anti-autoimmune neuropeptide.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis.
Proceedings of the National Academy of Sciences of the United States of America, 106(6), 2012-7
Citation
Tan, Yossan-Var; Abad, Catalina; Lopez, Robert; Dong, Hongmei; Liu, Shen; Lee, Alice; Gomariz, Rosa P; Leceta, Javier; Waschek, James A. (2009). Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis.. Proceedings of the National Academy of Sciences of the United States of America, 106(6), 2012-7. https://doi.org/10.1073/pnas.0812257106