A New Endomorphin-Like Peptide Discovered in the Rat Brain
A novel immunoreactive peptide related to endomorphin-2 was detected in rat brain extracts, potentially representing a new endogenous mu-opioid peptide or endomorphin precursor — expanding the known endogenous opioid repertoire.
Quick Facts
What This Study Found
A novel endomorphin-2-like immunoreactive peptide was detected in rat brain extracts with different chromatographic properties from known endomorphin-2, potentially representing a new endogenous mu-opioid peptide or modified form — expanding the endogenous opioid catalog.
Key Numbers
How They Did This
in-vitro study.
Why This Research Matters
Relevant for opioid-peptides, neuropeptides.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding A novel endomorphin-2-like immunoreactive peptide was detected in rat brain extracts with different chromatographic properties from known endomorphin-
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.
- Published In:
- Regulatory peptides, 148(1-3), 54-61 (2008)
- Authors:
- Szemenyei, Erzsébet, Barna, István, Mergl, Zsuzsa, Keresztes, Attila, Darula, Zsuzsanna, Kató, Erzsébet, Tóth, Géza, Rónai, András Z
- Database ID:
- RPEP-01425
Evidence Hierarchy
Frequently Asked Questions
What was studied?
A New Endomorphin-Like Peptide Discovered in the Rat Brain
What was found?
A novel immunoreactive peptide related to endomorphin-2 was detected in rat brain extracts, potentially representing a new endogenous mu-opioid peptide or endomorphin precursor — expanding the known endogenous opioid repertoire.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01425APA
Szemenyei, Erzsébet; Barna, István; Mergl, Zsuzsa; Keresztes, Attila; Darula, Zsuzsanna; Kató, Erzsébet; Tóth, Géza; Rónai, András Z. (2008). Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.. Regulatory peptides, 148(1-3), 54-61. https://doi.org/10.1016/j.regpep.2008.03.001
MLA
Szemenyei, Erzsébet, et al. "Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.." Regulatory peptides, 2008. https://doi.org/10.1016/j.regpep.2008.03.001
RethinkPeptides
RethinkPeptides Research Database. "Detection of a novel immunoreactive endomorphin 2-like pepti..." RPEP-01425. Retrieved from https://rethinkpeptides.com/research/szemenyei-2008-detection-of-a-novel
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.