A novel immunoreactive peptide related to endomorphin-2 was detected in rat brain extracts, potentially representing a new endogenous mu-opioid peptide or endomorphin precursor — expanding the known endogenous opioid repertoire.
Key findingA novel endomorphin-2-like immunoreactive peptide was detected in rat brain extracts with different chromatographic properties from known endomorphin-
What the researchers found
A novel endomorphin-2-like immunoreactive peptide was detected in rat brain extracts with different chromatographic properties from known endomorphin-2, potentially representing a new endogenous mu-opioid peptide or modified form — expanding the endogenous opioid catalog.
Why it matters
Relevant for opioid-peptides, neuropeptides.
How the study worked
in-vitro study.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2008.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.
Regulatory peptides, 148(1-3), 54-61
Citation
Szemenyei, Erzsébet; Barna, István; Mergl, Zsuzsa; Keresztes, Attila; Darula, Zsuzsanna; Kató, Erzsébet; Tóth, Géza; Rónai, András Z. (2008). Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.. Regulatory peptides, 148(1-3), 54-61. https://doi.org/10.1016/j.regpep.2008.03.001