Metabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding design of longer-lasting antimicrobial peptide drugs.
Key findingMetabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding
What the researchers found
Metabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding design of longer-lasting antimicrobial peptide drugs.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Metabolic fate of lactoferricin-based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability.
The Journal of pharmacology and experimental therapeutics, 332(3), 1032-9
Citation
Svenson, Johan; Vergote, Valentijn; Karstad, Rasmus; Burvenich, Christian; Svendsen, John S; De Spiegeleer, Bart. (2010). Metabolic fate of lactoferricin-based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability.. The Journal of pharmacology and experimental therapeutics, 332(3), 1032-9. https://doi.org/10.1124/jpet.109.162826