How Fast Do Antimicrobial Lactoferricin Peptides Break Down in the Body?
Metabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding design of longer-lasting antimicrobial peptide drugs.
Quick Facts
What This Study Found
Metabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding design of longer-lasting antimicrobial peptide drugs.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
Trust & Context
- Key Stat:
- Key finding Metabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2010.
- Original Title:
- Metabolic fate of lactoferricin-based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability.
- Published In:
- The Journal of pharmacology and experimental therapeutics, 332(3), 1032-9 (2010)
- Authors:
- Svenson, Johan, Vergote, Valentijn, Karstad, Rasmus, Burvenich, Christian, Svendsen, John S, De Spiegeleer, Bart
- Database ID:
- RPEP-01700
Evidence Hierarchy
Frequently Asked Questions
What was studied?
How Fast Do Antimicrobial Lactoferricin Peptides Break Down in the Body?
What was found?
Metabolic fate studies of lactoferricin-based peptides revealed truncation and amino acid analog incorporation improve proteolytic stability — guiding design of longer-lasting antimicrobial peptide drugs.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01700APA
Svenson, Johan; Vergote, Valentijn; Karstad, Rasmus; Burvenich, Christian; Svendsen, John S; De Spiegeleer, Bart. (2010). Metabolic fate of lactoferricin-based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability.. The Journal of pharmacology and experimental therapeutics, 332(3), 1032-9. https://doi.org/10.1124/jpet.109.162826
MLA
Svenson, Johan, et al. "Metabolic fate of lactoferricin-based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability.." The Journal of pharmacology and experimental therapeutics, 2010. https://doi.org/10.1124/jpet.109.162826
RethinkPeptides
RethinkPeptides Research Database. "Metabolic fate of lactoferricin-based antimicrobial peptides..." RPEP-01700. Retrieved from https://rethinkpeptides.com/research/svenson-2010-metabolic-fate-of-lactoferricinbased
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.