Gastric X/A-like cells co-produce ghrelin (appetite-stimulating), des-acyl ghrelin (metabolically active), and nesfatin-1 (appetite-suppressing) — three functionally different peptides from a single endocrine cell type.
Key findingGastric X/A-like cells co-produce ghrelin (appetite-stimulating), des-acyl ghrelin (metabolically active), and nesfatin-1 (appetite-suppressing) — thr
What the researchers found
Gastric X/A-like cells co-produce ghrelin (appetite-stimulating), des-acyl ghrelin (metabolically active), and nesfatin-1 (appetite-suppressing) — three functionally different peptides from a single endocrine cell type.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight.
Peptides, 31(2), 357-69
Citation
Stengel, Andreas; Goebel, Miriam; Wang, Lixin; Taché, Yvette. (2010). Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight.. Peptides, 31(2), 357-69. https://doi.org/10.1016/j.peptides.2009.11.019