The BTBR autism model mouse showed reduced stress reactivity and altered neuroendocrine factors (oxytocin, vasopressin, CRF), linking neuropeptide dysregulation to autism-like social behavior deficits.
Key findingThe BTBR autism model mouse showed reduced stress reactivity and altered neuroendocrine factors (oxytocin, vasopressin, CRF), linking neuropeptide dys
What the researchers found
The BTBR autism model mouse showed reduced stress reactivity and altered neuroendocrine factors (oxytocin, vasopressin, CRF), linking neuropeptide dysregulation to autism-like social behavior deficits.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism.
Neuroscience, 171(4), 1197-208
Citation
Silverman, J L; Yang, M; Turner, S M; Katz, A M; Bell, D B; Koenig, J I; Crawley, J N. (2010). Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism.. Neuroscience, 171(4), 1197-208. https://doi.org/10.1016/j.neuroscience.2010.09.059