What Controls Ghrelin Release From the Stomach: Nutrients, Nerves, and Hormones

Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose and insulin suppressing and acetylcholine stimulating release.

Shrestha, Yogendra B et al.·Peptides·2009·
RPEP-015472009RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose and insulin suppressing and acetylcholine stimulating release.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose a
Evidence Grade:
emerging evidence.
Study Age:
Published in 2009.
Original Title:
Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats.
Published In:
Peptides, 30(6), 1187-91 (2009)
Database ID:
RPEP-01547

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

What Controls Ghrelin Release From the Stomach: Nutrients, Nerves, and Hormones

What was found?

Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose and insulin suppressing and acetylcholine stimulating release.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01547·https://rethinkpeptides.com/research/RPEP-01547

APA

Shrestha, Yogendra B; Wickwire, Kathie; Giraudo, Silvia Q. (2009). Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats.. Peptides, 30(6), 1187-91. https://doi.org/10.1016/j.peptides.2009.02.001

MLA

Shrestha, Yogendra B, et al. "Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats.." Peptides, 2009. https://doi.org/10.1016/j.peptides.2009.02.001

RethinkPeptides

RethinkPeptides Research Database. "Direct effects of nutrients, acetylcholine, CCK, and insulin..." RPEP-01547. Retrieved from https://rethinkpeptides.com/research/shrestha-2009-direct-effects-of-nutrients

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.