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Study breakdown

What Controls Ghrelin Release From the Stomach: Nutrients, Nerves, and Hormones

evidence
The takeaway

Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose and insulin suppressing and acetylcholine stimulating release.

Key finding

Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose a

What the researchers found

Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose and insulin suppressing and acetylcholine stimulating release.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
What Controls Ghrelin Release From the Stomach: Nutrients, Nerves, and Hormones
What was found?
Direct isolated stomach studies revealed nutrients (glucose), acetylcholine, CCK, and insulin each directly regulate ghrelin secretion, with glucose and insulin suppressing and acetylcholine stimulating release.

Read the original research

Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats.

Peptides, 30(6), 1187-91

Citation

Shrestha, Yogendra B; Wickwire, Kathie; Giraudo, Silvia Q. (2009). Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats.. Peptides, 30(6), 1187-91. https://doi.org/10.1016/j.peptides.2009.02.001