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Study breakdown

Smaller Fat Droplets in the Gut Trigger Stronger Satiety Hormone Release

evidence
The takeaway

Smaller intraduodenal fat emulsion droplets produced greater CCK and GLP-1 release and stronger appetite suppression in humans, demonstrating that food processing (particle size) determines satiety hormone response.

Key finding

Smaller intraduodenal fat emulsion droplets produced greater CCK and GLP-1 release and stronger appetite suppression in humans, demonstrating that foo

What the researchers found

Smaller intraduodenal fat emulsion droplets produced greater CCK and GLP-1 release and stronger appetite suppression in humans, demonstrating that food processing (particle size) determines satiety hormone response.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Smaller Fat Droplets in the Gut Trigger Stronger Satiety Hormone Release
What was found?
Smaller intraduodenal fat emulsion droplets produced greater CCK and GLP-1 release and stronger appetite suppression in humans, demonstrating that food processing (particle size) determines satiety hormone response.

Read the original research

The droplet size of intraduodenal fat emulsions influences antropyloroduodenal motility, hormone release, and appetite in healthy males.

The American journal of clinical nutrition, 89(6), 1729-36

Citation

Seimon, Radhika V; Wooster, Timothy; Otto, Bärbel; Golding, Matthew; Day, Li; Little, Tanya J; Horowitz, Michael; Clifton, Peter M; Feinle-Bisset, Christine. (2009). The droplet size of intraduodenal fat emulsions influences antropyloroduodenal motility, hormone release, and appetite in healthy males.. The American journal of clinical nutrition, 89(6), 1729-36. https://doi.org/10.3945/ajcn.2009.27518