Lactoferrin-derived peptides inhibited complement activation, adding anti-complement activity to lactoferricin's already diverse antimicrobial and immunomodulatory portfolio.
Key findingLactoferrin-derived peptides showed anti-complement activity, inhibiting complement cascade activation and adding immune modulation beyond antimicrobi
What the researchers found
Lactoferrin-derived peptides showed anti-complement activity, inhibiting complement cascade activation and adding immune modulation beyond antimicrobial effects to the lactoferricin functional profile.
Why it matters
Relevant for antimicrobial-peptides, immune-function, inflammation.
How the study worked
in-vitro study on antimicrobial-peptides, immune-function.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2004.
The bigger picture
Advances peptide therapeutics research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Anti-complement effects of lactoferrin-derived peptides.
FEMS immunology and medical microbiology, 41(2), 141-8
Citation
Samuelsen, Ørjan; Haukland, Hanne H; Ulvatne, Hilde; Vorland, Lars H. (2004). Anti-complement effects of lactoferrin-derived peptides.. FEMS immunology and medical microbiology, 41(2), 141-8.