Lactoferrin-Derived Peptides Suppress the Complement Immune System
Lactoferrin-derived peptides inhibited complement activation, adding anti-complement activity to lactoferricin's already diverse antimicrobial and immunomodulatory portfolio.
Quick Facts
What This Study Found
Lactoferrin-derived peptides showed anti-complement activity, inhibiting complement cascade activation and adding immune modulation beyond antimicrobial effects to the lactoferricin functional profile.
Key Numbers
How They Did This
in-vitro study on antimicrobial-peptides, immune-function.
Why This Research Matters
Relevant for antimicrobial-peptides, immune-function, inflammation.
The Bigger Picture
Advances peptide therapeutics research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Lactoferrin-derived peptides showed anti-complement activity, inhibiting complement cascade activation and adding immune modulation beyond antimicrobi
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2004.
- Original Title:
- Anti-complement effects of lactoferrin-derived peptides.
- Published In:
- FEMS immunology and medical microbiology, 41(2), 141-8 (2004)
- Authors:
- Samuelsen, Ørjan(2), Haukland, Hanne H(3), Ulvatne, Hilde(4), Vorland, Lars H
- Database ID:
- RPEP-00972
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Lactoferrin-Derived Peptides Suppress the Complement Immune System
What was found?
Lactoferrin-derived peptides inhibited complement activation, adding anti-complement activity to lactoferricin's already diverse antimicrobial and immunomodulatory portfolio.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-00972APA
Samuelsen, Ørjan; Haukland, Hanne H; Ulvatne, Hilde; Vorland, Lars H. (2004). Anti-complement effects of lactoferrin-derived peptides.. FEMS immunology and medical microbiology, 41(2), 141-8.
MLA
Samuelsen, Ørjan, et al. "Anti-complement effects of lactoferrin-derived peptides.." FEMS immunology and medical microbiology, 2004.
RethinkPeptides
RethinkPeptides Research Database. "Anti-complement effects of lactoferrin-derived peptides." RPEP-00972. Retrieved from https://rethinkpeptides.com/research/samuelsen-2004-anticomplement-effects-of-lactoferrinderived
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.