SHP-1, a novel seahorse-derived peptide, suppressed collagenases (MMP-1, MMP-13) and gelatinase (MMP-9), potentially protecting joint cartilage from destruction in arthritis — marine peptide therapy for joint disease.
Key findingSHP-1, a novel seahorse-derived peptide, suppressed collagenases (MMP-1, MMP-13) and gelatinase (MMP-9), potentially protecting joint cartilage from d
What the researchers found
SHP-1, a novel seahorse-derived peptide, suppressed collagenases (MMP-1, MMP-13) and gelatinase (MMP-9), potentially protecting joint cartilage from destruction in arthritis — marine peptide therapy for joint disease.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
SHP-1, a novel peptide isolated from seahorse inhibits collagen release through the suppression of collagenases 1 and 3, nitric oxide products regulated by NF-kappaB/p38 kinase.
Peptides, 31(1), 79-87
Citation
Ryu, BoMi; Qian, Zhong-Ji; Kim, Se-Kwon. (2010). SHP-1, a novel peptide isolated from seahorse inhibits collagen release through the suppression of collagenases 1 and 3, nitric oxide products regulated by NF-kappaB/p38 kinase.. Peptides, 31(1), 79-87. https://doi.org/10.1016/j.peptides.2009.10.019