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Study breakdown

Seahorse Peptide Blocks Inflammation Through MAPK and NF-κB Pathways

evidence
The takeaway

A purified seahorse-derived peptide inhibited MMP, iNOS, and COX-2 inflammatory mediators through MAPK and NF-κB pathway suppression — a marine-derived anti-inflammatory peptide with arthritis potential.

Key finding

A purified seahorse-derived peptide inhibited MMP, iNOS, and COX-2 inflammatory mediators through MAPK and NF-κB pathway suppression — a marine-derive

What the researchers found

A purified seahorse-derived peptide inhibited MMP, iNOS, and COX-2 inflammatory mediators through MAPK and NF-κB pathway suppression — a marine-derived anti-inflammatory peptide with arthritis potential.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Seahorse Peptide Blocks Inflammation Through MAPK and NF-κB Pathways
What was found?
A purified seahorse-derived peptide inhibited MMP, iNOS, and COX-2 inflammatory mediators through MAPK and NF-κB pathway suppression — a marine-derived anti-inflammatory peptide with arthritis potential.

Read the original research

Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation.

Chemico-biological interactions, 184(3), 413-22

Citation

Ryu, BoMi; Qian, Zhong-Ji; Kim, Se-Kwon. (2010). Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation.. Chemico-biological interactions, 184(3), 413-22. https://doi.org/10.1016/j.cbi.2009.12.003