Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice.
Quick Facts
What This Study Found
SS-31 improved mitochondrial respiratory capacity in TazKD mice without affecting the MLCL/CL ratio.
Key Numbers
How They Did This
The study used TAFAZZIN knockdown mice to assess the impact of SS-31 on mitochondrial function and lipid profiles.
Why This Research Matters
Improving mitochondrial function could lead to better treatments for Barth Syndrome, a condition with limited therapeutic options. This research highlights the potential of SS-31 as a pharmacological agent.
What This Study Doesn't Tell Us
The study was conducted in mice, and results may not directly translate to humans. Further research is needed to confirm these findings in clinical settings.
Trust & Context
- Original Title:
- Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice.
- Published In:
- Scientific reports, 12(1), 19847 (2022)
- Database ID:
- RPEP-06467
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06467APA
Russo, Silvia; De Rasmo, Domenico; Signorile, Anna; Corcelli, Angela; Lobasso, Simona. (2022). Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice.. Scientific reports, 12(1), 19847. https://doi.org/10.1038/s41598-022-24231-4
MLA
Russo, Silvia, et al. "Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice.." Scientific reports, 2022. https://doi.org/10.1038/s41598-022-24231-4
RethinkPeptides
RethinkPeptides Research Database. "Beneficial effects of SS-31 peptide on cardiac mitochondrial..." RPEP-06467. Retrieved from https://rethinkpeptides.com/research/russo-2022-beneficial-effects-of-ss31
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.