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Neuropeptides in Animal Models of Depression and Anxiety: CRF, NPY, and the Therapeutic Landscape

evidence
The takeaway

Comprehensive review of neuropeptide behavioral effects in depression and anxiety rodent models: CRF antagonists for anxiolysis, NPY agonists for resilience, and other peptide targets — guiding psychiatric drug development.

Key finding

Comprehensive review of neuropeptide behavioral effects in depression and anxiety rodent models: CRF antagonists for anxiolysis, NPY agonists for resi

What the researchers found

Comprehensive review of neuropeptide behavioral effects in depression and anxiety rodent models: CRF antagonists for anxiolysis, NPY agonists for resilience, and other peptide targets — guiding psychiatric drug development.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Neuropeptides in Animal Models of Depression and Anxiety: CRF, NPY, and the Therapeutic Landscape
What was found?
Comprehensive review of neuropeptide behavioral effects in depression and anxiety rodent models: CRF antagonists for anxiolysis, NPY agonists for resilience, and other peptide targets — guiding psychiatric drug development.

Read the original research

Behavioral effects of neuropeptides in rodent models of depression and anxiety.

Peptides, 31(4), 736-56

Citation

Rotzinger, Susan; Lovejoy, David A; Tan, Laura A. (2010). Behavioral effects of neuropeptides in rodent models of depression and anxiety.. Peptides, 31(4), 736-56. https://doi.org/10.1016/j.peptides.2009.12.015