Mycobacteria activated formyl peptide receptors on neutrophils to release opioid peptides, providing local pain relief during infection — bacteria inadvertently trigger the host's own pain control system.
Key findingMycobacteria activated formyl peptide receptors on neutrophils to release opioid peptides, providing local pain relief during infection — bacteria ina
What the researchers found
Mycobacteria activated formyl peptide receptors on neutrophils to release opioid peptides, providing local pain relief during infection — bacteria inadvertently trigger the host's own pain control system.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils.
PLoS pathogens, 5(4), e1000362
Citation
Rittner, Heike L; Hackel, Dagmar; Voigt, Philipp; Mousa, Shaaban; Stolz, Andrea; Labuz, Dominika; Schäfer, Michael; Schaefer, Michael; Stein, Christoph; Brack, Alexander. (2009). Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils.. PLoS pathogens, 5(4), e1000362. https://doi.org/10.1371/journal.ppat.1000362