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Study breakdown

Long-Term Calorie Restriction Changes Ghrelin and Its Processing Enzyme GOAT

evidence
The takeaway

Chronic dietary restriction altered both plasma ghrelin levels and GOAT (the enzyme that activates ghrelin by adding its fatty acid tag) mRNA in rats — calorie restriction reprograms the ghrelin activation system.

Key finding

Chronic dietary restriction altered both plasma ghrelin levels and GOAT (the enzyme that activates ghrelin by adding its fatty acid tag) mRNA in rats

What the researchers found

Chronic dietary restriction altered both plasma ghrelin levels and GOAT (the enzyme that activates ghrelin by adding its fatty acid tag) mRNA in rats — calorie restriction reprograms the ghrelin activation system.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Long-Term Calorie Restriction Changes Ghrelin and Its Processing Enzyme GOAT
What was found?
Chronic dietary restriction altered both plasma ghrelin levels and GOAT (the enzyme that activates ghrelin by adding its fatty acid tag) mRNA in rats — calorie restriction reprograms the ghrelin activation system.

Read the original research

Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats.

Physiology & behavior, 99(5), 605-10

Citation

Reimer, Raylene A; Maurer, Alannah D; Lau, David C W; Auer, Roland N. (2010). Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats.. Physiology & behavior, 99(5), 605-10. https://doi.org/10.1016/j.physbeh.2010.01.034