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Research citation

Long term effects of chronic intranasal oxytocin on adult pair bonding behavior and brain glucose uptake in titi monkeys (Plecturocebus cupreus).

evidence

This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.

What the researchers found

OXT-treated monkeys showed increased affiliative behaviors, particularly tail twining, compared to saline-treated monkeys.

Why it matters

Understanding the effects of oxytocin on social behavior could inform treatments for social deficits in humans. This research may have implications for neurodevelopmental disorders.

How the study worked

The study involved administering intranasal oxytocin or saline to titi monkeys for six months, followed by behavioral observations and PET scans one year later.

What this study cannot tell us

The study was conducted on a small sample size and in a specific species, which may limit generalizability to humans.

Read the original research

Long term effects of chronic intranasal oxytocin on adult pair bonding behavior and brain glucose uptake in titi monkeys (Plecturocebus cupreus).

Hormones and behavior, 140, 105126

Citation

Razo, Rocío Arias-Del; Velasco Vazquez, Maria de Lourdes; Turcanu, Petru; Legrand, Mathieu; Floch, Maeva; Weinstein, Tamara A R; Goetze, Leana R; Freeman, Sara M; Baxter, Alexander; Witczak, Lynea R; Sahagún, Elizabeth; Berger, Trish; Jacob, Suma; Lawrence, Rebecca H; Rothwell, Emily S; Savidge, Logan E; Solomon, Marjorie; Mendoza, Sally P; Bales, Karen L. (2022). Long term effects of chronic intranasal oxytocin on adult pair bonding behavior and brain glucose uptake in titi monkeys (Plecturocebus cupreus).. Hormones and behavior, 140, 105126. https://doi.org/10.1016/j.yhbeh.2022.105126