Endothelin B Receptor Activation Produces Pain Relief Through Endogenous Opioid Release

Peripheral endothelin B receptor agonists produced pain relief in mice through triggering endogenous opioid peptide release — another non-opioid drug that works by enlisting the body's own painkillers.

Quang, Phuong N et al.·Pain·2010·
RPEP-016782010RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Peripheral endothelin B receptor agonists produced pain relief in mice through triggering endogenous opioid peptide release — another non-opioid drug that works by enlisting the body's own painkillers.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding Peripheral endothelin B receptor agonists produced pain relief in mice through triggering endogenous opioid peptide release — another non-opioid drug
Evidence Grade:
emerging evidence.
Study Age:
Published in 2010.
Original Title:
Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in mice.
Published In:
Pain, 149(2), 254-262 (2010)
Database ID:
RPEP-01678

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Endothelin B Receptor Activation Produces Pain Relief Through Endogenous Opioid Release

What was found?

Peripheral endothelin B receptor agonists produced pain relief in mice through triggering endogenous opioid peptide release — another non-opioid drug that works by enlisting the body's own painkillers.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01678·https://rethinkpeptides.com/research/RPEP-01678

APA

Quang, Phuong N; Schmidt, Brian L. (2010). Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in mice.. Pain, 149(2), 254-262. https://doi.org/10.1016/j.pain.2010.02.009

MLA

Quang, Phuong N, et al. "Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in mice.." Pain, 2010. https://doi.org/10.1016/j.pain.2010.02.009

RethinkPeptides

RethinkPeptides Research Database. "Peripheral endothelin B receptor agonist-induced antinocicep..." RPEP-01678. Retrieved from https://rethinkpeptides.com/research/quang-2010-peripheral-endothelin-b-receptor

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.