Adults with Prader-Willi syndrome had elevated ghrelin more consistently than altered PYY/GLP-1, with high ghrelin better explaining the hyperphagia (extreme eating) than satiety peptide changes.
Key findingAdults with Prader-Willi syndrome had elevated ghrelin more consistently than altered PYY/GLP-1, with high ghrelin better explaining the hyperphagia (
What the researchers found
Adults with Prader-Willi syndrome had elevated ghrelin more consistently than altered PYY/GLP-1, with high ghrelin better explaining the hyperphagia (extreme eating) than satiety peptide changes.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
In adults with Prader-Willi syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels.
Neuropeptides, 45(4), 301-7
Citation
Purtell, Louise; Sze, Lisa; Loughnan, Georgina; Smith, Ellie; Herzog, Herbert; Sainsbury, Amanda; Steinbeck, Katharine; Campbell, Lesley V; Viardot, Alexander. (2011). In adults with Prader-Willi syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels.. Neuropeptides, 45(4), 301-7. https://doi.org/10.1016/j.npep.2011.06.001