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Research citation

Characterization of growth hormone secretagogue small molecule ibutamoren (MK-0677) and its possible metabolites in thoroughbred horses for doping control.

evidence

This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.

What the researchers found

22 metabolites of ibutamoren were identified, detectable for up to 96 hours.

Why it matters

Understanding how ibutamoren metabolizes helps improve doping control in competitive sports. This knowledge can help ensure fair competition by identifying illegal substance use.

How the study worked

The study used liquid chromatography and high-resolution mass spectrometry to analyze ibutamoren and its metabolites in thoroughbred horses after oral administration.

What this study cannot tell us

The study is limited to thoroughbred horses, and results may not directly apply to other species or humans.

Read the original research

Characterization of growth hormone secretagogue small molecule ibutamoren (MK-0677) and its possible metabolites in thoroughbred horses for doping control.

Rapid communications in mass spectrometry : RCM, 36(18), e9337

Citation

Philip, Moses; Karakka Kal, Abdul Khader; Subhahar, Michael Benedict; Karatt, Tajudheen K; Mathew, Binoy; Koshy, Shino Ann. (2022). Characterization of growth hormone secretagogue small molecule ibutamoren (MK-0677) and its possible metabolites in thoroughbred horses for doping control.. Rapid communications in mass spectrometry : RCM, 36(18), e9337. https://doi.org/10.1002/rcm.9337