PT-141 Melanocortin Agonist Selectively Enhances Female Sexual Desire in Rats
PT-141 selectively facilitated sexual solicitation behavior in female rats without affecting other behaviors, confirming melanocortin receptors specifically modulate female sexual desire — supporting development for women's sexual dysfunction.
Quick Facts
What This Study Found
PT-141 (melanocortin agonist) selectively increased sexual solicitation (proceptive) behavior in female rats without affecting locomotion or other behaviors — demonstrating specific melanocortin modulation of female sexual desire/motivation.
Key Numbers
How They Did This
animal-study study on pt-141, sexual-health.
Why This Research Matters
Relevant for pt-141, sexual-health, receptor-signaling, clinical-trials.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding PT-141 (melanocortin agonist) selectively increased sexual solicitation (proceptive) behavior in female rats without affecting locomotion or other beh
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2004.
- Original Title:
- Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist.
- Published In:
- Proceedings of the National Academy of Sciences of the United States of America, 101(27), 10201-4 (2004)
- Database ID:
- RPEP-00959
Evidence Hierarchy
Tests effects in animals (usually mice or rats), not humans.
What do these levels mean? →Frequently Asked Questions
What was studied?
PT-141 Melanocortin Agonist Selectively Enhances Female Sexual Desire in Rats
What was found?
PT-141 selectively facilitated sexual solicitation behavior in female rats without affecting other behaviors, confirming melanocortin receptors specifically modulate female sexual desire — supporting development for women's sexual dysfunction.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-00959APA
Pfaus, James G; Shadiack, Annette; Van Soest, Tanya; Tse, Maric; Molinoff, Perry. (2004). Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist.. Proceedings of the National Academy of Sciences of the United States of America, 101(27), 10201-4.
MLA
Pfaus, James G, et al. "Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist.." Proceedings of the National Academy of Sciences of the United States of America, 2004.
RethinkPeptides
RethinkPeptides Research Database. "Selective facilitation of sexual solicitation in the female ..." RPEP-00959. Retrieved from https://rethinkpeptides.com/research/pfaus-2004-selective-facilitation-of-sexual
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.