Stress-Induced Pain Relief Depends on Stress Duration: Different Timescales Activate Different Opioids

The duration of stress determined which endogenous opioid system mediated stress-induced analgesia — short stress used non-opioid mechanisms while prolonged stress recruited endogenous opioid peptide release.

Parikh, Drupad et al.·European journal of pharmacology·2011·
RPEP-018332011RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

The duration of stress determined which endogenous opioid system mediated stress-induced analgesia — short stress used non-opioid mechanisms while prolonged stress recruited endogenous opioid peptide release.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding The duration of stress determined which endogenous opioid system mediated stress-induced analgesia — short stress used non-opioid mechanisms while pro
Evidence Grade:
emerging evidence.
Study Age:
Published in 2011.
Original Title:
Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration.
Published In:
European journal of pharmacology, 650(2-3), 563-7 (2011)
Database ID:
RPEP-01833

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Stress-Induced Pain Relief Depends on Stress Duration: Different Timescales Activate Different Opioids

What was found?

The duration of stress determined which endogenous opioid system mediated stress-induced analgesia — short stress used non-opioid mechanisms while prolonged stress recruited endogenous opioid peptide release.

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Cite This Study

RPEP-01833·https://rethinkpeptides.com/research/RPEP-01833

APA

Parikh, Drupad; Hamid, Abdul; Friedman, Theodore C; Nguyen, Khanh; Tseng, Andy; Marquez, Paul; Lutfy, Kabirullah. (2011). Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration.. European journal of pharmacology, 650(2-3), 563-7. https://doi.org/10.1016/j.ejphar.2010.10.050

MLA

Parikh, Drupad, et al. "Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration.." European journal of pharmacology, 2011. https://doi.org/10.1016/j.ejphar.2010.10.050

RethinkPeptides

RethinkPeptides Research Database. "Stress-induced analgesia and endogenous opioid peptides: the..." RPEP-01833. Retrieved from https://rethinkpeptides.com/research/parikh-2011-stressinduced-analgesia-and-endogenous

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.