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Study breakdown

Aldosterone Levels During Heart Attack Hospitalization Predict Long-Term Survival

CohortModerate evidence
The takeaway

Plasma aldosterone measured during MI hospitalization independently predicted post-infarction survival, adding this mineralocorticoid hormone to the biomarker panel for MI risk stratification.

Key finding

Plasma aldosterone levels during MI hospitalization independently predicted post-discharge survival, with higher aldosterone indicating worse prognosi

What the researchers found

Plasma aldosterone levels during MI hospitalization independently predicted post-discharge survival, with higher aldosterone indicating worse prognosis — adding aldosterone to BNP and other neurohormones for comprehensive post-MI risk stratification.

Why it matters

Relevant for cardiovascular.

How the study worked

cohort study.

What this study cannot tell us

See abstract.

How to read the evidence

moderate evidence.

When this study was published

Published in 2008.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.
  • Clinical translation to evaluate.

Common questions

What was studied?
Aldosterone Levels During Heart Attack Hospitalization Predict Long-Term Survival
What was found?
Plasma aldosterone measured during MI hospitalization independently predicted post-infarction survival, adding this mineralocorticoid hormone to the biomarker panel for MI risk stratification.

Read the original research

Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction.

European heart journal, 29(20), 2489-96

Citation

Palmer, Barry R; Pilbrow, Anna P; Frampton, Christopher M; Yandle, Tim G; Skelton, Lorraine; Nicholls, M Gary; Richards, A Mark. (2008). Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction.. European heart journal, 29(20), 2489-96. https://doi.org/10.1093/eurheartj/ehn383