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Synthesis and evaluation of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydromorphinone derivatives: mixed partial agonists at mu opioid and nociception/orphanin FQ peptide receptors.

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Synthesis and evaluation of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydromorphinone derivatives: mixed partial agonists at mu opioid and nociception/orphanin FQ peptide receptors.

RSC medicinal chemistry

Citation

Ostovar, Mehrnoosh; Olsen, Keith; Cami-Kobeci, Gerta; Traynor, John R; Jeramaz, Luka; Kirton, Stewart B; Husbands, Stephen M. (2026). Synthesis and evaluation of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydromorphinone derivatives: mixed partial agonists at mu opioid and nociception/orphanin FQ peptide receptors.. RSC medicinal chemistry. https://doi.org/10.1039/d5md00685f