PYY3-36 Also Affects Thyroid Hormone: The Gut Satiety Peptide Modulates TSH Secretion
PYY3-36 modulated TSH (thyroid-stimulating hormone) secretion in rats, revealing a previously unknown connection between the gut satiety peptide system and thyroid regulation.
Quick Facts
What This Study Found
PYY3-36 modulated thyrotropin (TSH) secretion in rats through hypothalamic/pituitary pathways, revealing a novel gut peptide-thyroid axis connection — the satiety system influences thyroid function beyond just appetite control.
Key Numbers
How They Did This
animal-study study on neuropeptides, hormone-optimization.
Why This Research Matters
Relevant for neuropeptides, hormone-optimization.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding PYY3-36 modulated thyrotropin (TSH) secretion in rats through hypothalamic/pituitary pathways, revealing a novel gut peptide-thyroid axis connection —
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Peptide YY (PYY)3-36 modulates thyrotropin secretion in rats.
- Published In:
- The Journal of endocrinology, 191(2), 459-63 (2006)
- Authors:
- Oliveira, K J, Paula, G S M, Costa-e-Sousa, R H, Souza, L L, Moraes, D C, Curty, F H, Pazos-Moura, C C
- Database ID:
- RPEP-01176
Evidence Hierarchy
Tests effects in animals (usually mice or rats), not humans.
What do these levels mean? →Frequently Asked Questions
What was studied?
PYY3-36 Also Affects Thyroid Hormone: The Gut Satiety Peptide Modulates TSH Secretion
What was found?
PYY3-36 modulated TSH (thyroid-stimulating hormone) secretion in rats, revealing a previously unknown connection between the gut satiety peptide system and thyroid regulation.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01176APA
Oliveira, K J; Paula, G S M; Costa-e-Sousa, R H; Souza, L L; Moraes, D C; Curty, F H; Pazos-Moura, C C. (2006). Peptide YY (PYY)3-36 modulates thyrotropin secretion in rats.. The Journal of endocrinology, 191(2), 459-63.
MLA
Oliveira, K J, et al. "Peptide YY (PYY)3-36 modulates thyrotropin secretion in rats.." The Journal of endocrinology, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Peptide YY (PYY)3-36 modulates thyrotropin secretion in rats..." RPEP-01176. Retrieved from https://rethinkpeptides.com/research/oliveira-2006-peptide-yy-pyy336-modulates
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.