Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by lactoferricin.
Quick Facts
What This Study Found
Lactoferricin and pLF1 inhibited TMPRSS2 activity and SARS-CoV-2 infection.
Key Numbers
How They Did This
The study tested lactoferricin and synthetic peptides for their ability to block TMPRSS2 and SARS-CoV-2 infection in laboratory conditions.
Why This Research Matters
As COVID-19 continues to pose a global health threat, finding effective antiviral therapies is crucial. This research highlights potential new treatments that could complement existing vaccines.
What This Study Doesn't Tell Us
The study was conducted in vitro, so results may not directly translate to clinical effectiveness in humans.
Trust & Context
- Original Title:
- Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by lactoferricin.
- Published In:
- Frontiers in immunology, 13, 958581 (2022)
- Authors:
- Ohradanova-Repic, Anna, Skrabana, Rostislav, Gebetsberger, Laura, Tajti, Gabor, Baráth, Peter, Ondrovičová, Gabriela, Praženicová, Romana, Jantova, Nikola, Hrasnova, Patricia, Stockinger, Hannes, Leksa, Vladimir
- Database ID:
- RPEP-06407
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06407APA
Ohradanova-Repic, Anna; Skrabana, Rostislav; Gebetsberger, Laura; Tajti, Gabor; Baráth, Peter; Ondrovičová, Gabriela; Praženicová, Romana; Jantova, Nikola; Hrasnova, Patricia; Stockinger, Hannes; Leksa, Vladimir. (2022). Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by lactoferricin.. Frontiers in immunology, 13, 958581. https://doi.org/10.3389/fimmu.2022.958581
MLA
Ohradanova-Repic, Anna, et al. "Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by lactoferricin.." Frontiers in immunology, 2022. https://doi.org/10.3389/fimmu.2022.958581
RethinkPeptides
RethinkPeptides Research Database. "Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by lactof..." RPEP-06407. Retrieved from https://rethinkpeptides.com/research/ohradanova-repic-2022-blockade-of-tmprss2mediated-priming
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.