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Study breakdown

NT-proBNP Is More Reliable Than BNP During Natriuretic Peptide Drug Infusion

evidence
The takeaway

NT-proBNP more accurately reflected cardiac status during carperitide (ANP analog) infusion than BNP, because BNP levels are directly affected by the drug while NT-proBNP is not — important for monitoring natriuretic peptide therapy.

Key finding

NT-proBNP more accurately reflected cardiac status during carperitide (ANP analog) infusion than BNP, because BNP levels are directly affected by the

What the researchers found

NT-proBNP more accurately reflected cardiac status during carperitide (ANP analog) infusion than BNP, because BNP levels are directly affected by the drug while NT-proBNP is not — important for monitoring natriuretic peptide therapy.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
NT-proBNP Is More Reliable Than BNP During Natriuretic Peptide Drug Infusion
What was found?
NT-proBNP more accurately reflected cardiac status during carperitide (ANP analog) infusion than BNP, because BNP levels are directly affected by the drug while NT-proBNP is not — important for monitoring natriuretic peptide therapy.

Read the original research

Plasma NT-proBNP as a more reliable biomarker of endogenous cardiac natriuretic peptides than BNP during carperitide infusion.

International heart journal, 50(2), 183-90

Citation

Nishiyama, Keizo; Tsutamoto, Takayoshi; Tanaka, Toshinari; Fujii, Masanori; Yamamoto, Takashi; Yamaji, Masayuki; Horie, Minoru. (2009). Plasma NT-proBNP as a more reliable biomarker of endogenous cardiac natriuretic peptides than BNP during carperitide infusion.. International heart journal, 50(2), 183-90.