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Study breakdown

A Synthetic Peptide Binds a Non-Opioid Beta-Endorphin Receptor in the Brain

evidence
The takeaway

Synthetic peptide TPLVTLFK bound to a non-opioid beta-endorphin receptor on rat brain membranes, confirming the existence of non-classical opioid receptors that mediate endorphin effects beyond pain relief.

Key finding

Synthetic peptide TPLVTLFK bound to a non-opioid beta-endorphin receptor on rat brain membranes, confirming the existence of non-classical opioid rece

What the researchers found

Synthetic peptide TPLVTLFK bound to a non-opioid beta-endorphin receptor on rat brain membranes, confirming the existence of non-classical opioid receptors that mediate endorphin effects beyond pain relief.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
A Synthetic Peptide Binds a Non-Opioid Beta-Endorphin Receptor in the Brain
What was found?
Synthetic peptide TPLVTLFK bound to a non-opioid beta-endorphin receptor on rat brain membranes, confirming the existence of non-classical opioid receptors that mediate endorphin effects beyond pain relief.

Read the original research

Binding of synthetic peptide TPLVTLFK to nonopioid beta-endorphin receptor on rat brain membranes.

Journal of peptide science : an official publication of the European Peptide Society, 16(6), 263-8

Citation

Nekrasova, Yuliia N; Sadovnikov, Vladimir B; Zolotarev, Yury A; Navolotskaya, Elena V. (2010). Binding of synthetic peptide TPLVTLFK to nonopioid beta-endorphin receptor on rat brain membranes.. Journal of peptide science : an official publication of the European Peptide Society, 16(6), 263-8. https://doi.org/10.1002/psc.1231