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Study breakdown

Melanocortin Agonist Reduces Alcohol Consumption in Rats: MC Receptors in Addiction

evidence
The takeaway

A melanocortin (MC) receptor agonist reduced voluntary ethanol consumption in rats, establishing melanocortin receptor activation as a potential therapeutic approach for reducing alcohol intake in addiction.

Key finding

A melanocortin (MC) receptor agonist reduced voluntary ethanol consumption in rats, establishing melanocortin receptor activation as a potential thera

What the researchers found

A melanocortin (MC) receptor agonist reduced voluntary ethanol consumption in rats, establishing melanocortin receptor activation as a potential therapeutic approach for reducing alcohol intake in addiction.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Melanocortin Agonist Reduces Alcohol Consumption in Rats: MC Receptors in Addiction
What was found?
A melanocortin (MC) receptor agonist reduced voluntary ethanol consumption in rats, establishing melanocortin receptor activation as a potential therapeutic approach for reducing alcohol intake in addiction.

Read the original research

Assessment of voluntary ethanol consumption and the effects of a melanocortin (MC) receptor agonist on ethanol intake in mutant C57BL/6J mice lacking the MC-4 receptor.

Alcoholism, clinical and experimental research, 35(6), 1058-66

Citation

Navarro, Montserrat; Lerma-Cabrera, Jose M; Carvajal, Francisca; Lowery, Emily G; Cubero, Inmaculada; Thiele, Todd E. (2011). Assessment of voluntary ethanol consumption and the effects of a melanocortin (MC) receptor agonist on ethanol intake in mutant C57BL/6J mice lacking the MC-4 receptor.. Alcoholism, clinical and experimental research, 35(6), 1058-66. https://doi.org/10.1111/j.1530-0277.2011.01438.x