Adrenomedullin promotes tumor angiogenesis (blood supply formation) as a tumor progression factor, with anti-adrenomedullin strategies potentially inhibiting tumor growth by cutting off blood supply.
Key findingAdrenomedullin functions as a tumor progression factor primarily through angiogenesis promotion — stimulating tumor blood vessel formation, supporting
What the researchers found
Adrenomedullin functions as a tumor progression factor primarily through angiogenesis promotion — stimulating tumor blood vessel formation, supporting cancer growth, and providing a targetable vulnerability for anti-cancer strategies.
Why it matters
Relevant for neuropeptides, cancer.
How the study worked
review study on neuropeptides, cancer.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Adrenomedullin: a tumor progression factor via angiogenic control.
Current cancer drug targets, 6(7), 635-43
Citation
Nakamura, Misa; Han, Bo; Nunobiki, Osamu; Kakudo, Kennichi. (2006). Adrenomedullin: a tumor progression factor via angiogenic control.. Current cancer drug targets, 6(7), 635-43.