NK-1 Receptor Antagonists: Blocking Substance P for Pain, Nausea, Depression, and Inflammation

NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, depression, and inflammatory conditions — multi-indication potential.

Muñoz, M et al.·Current medicinal chemistry·2011·
RPEP-018212011RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, depression, and inflammatory conditions — multi-indication potential.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, dep
Evidence Grade:
emerging evidence.
Study Age:
Published in 2011.
Original Title:
NK-1 receptor antagonists: a new paradigm in pharmacological therapy.
Published In:
Current medicinal chemistry, 18(12), 1820-31 (2011)
Database ID:
RPEP-01821

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

NK-1 Receptor Antagonists: Blocking Substance P for Pain, Nausea, Depression, and Inflammation

What was found?

NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, depression, and inflammatory conditions — multi-indication potential.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01821·https://rethinkpeptides.com/research/RPEP-01821

APA

Muñoz, M; Coveñas, R. (2011). NK-1 receptor antagonists: a new paradigm in pharmacological therapy.. Current medicinal chemistry, 18(12), 1820-31.

MLA

Muñoz, M, et al. "NK-1 receptor antagonists: a new paradigm in pharmacological therapy.." Current medicinal chemistry, 2011.

RethinkPeptides

RethinkPeptides Research Database. "NK-1 receptor antagonists: a new paradigm in pharmacological..." RPEP-01821. Retrieved from https://rethinkpeptides.com/research/munoz-2011-nk1-receptor-antagonists-a

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.