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Study breakdown

NK-1 Receptor Antagonists: Blocking Substance P for Pain, Nausea, Depression, and Inflammation

evidence
The takeaway

NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, depression, and inflammatory conditions — multi-indication potential.

Key finding

NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, dep

What the researchers found

NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, depression, and inflammatory conditions — multi-indication potential.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
NK-1 Receptor Antagonists: Blocking Substance P for Pain, Nausea, Depression, and Inflammation
What was found?
NK-1 receptor antagonists (substance P blockers) represent a new pharmacological paradigm with applications in emesis (aprepitant approved), pain, depression, and inflammatory conditions — multi-indication potential.

Read the original research

NK-1 receptor antagonists: a new paradigm in pharmacological therapy.

Current medicinal chemistry, 18(12), 1820-31

Citation

Muñoz, M; Coveñas, R. (2011). NK-1 receptor antagonists: a new paradigm in pharmacological therapy.. Current medicinal chemistry, 18(12), 1820-31.